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Information card for entry 1557185
Preview
| Coordinates | 1557185.cif |
|---|---|
| Original paper (by DOI) | HTML |
| Formula | C25 H23 F4 N5 O5 |
|---|---|
| Calculated formula | C25 H23 F4 N5 O5 |
| Title of publication | Discovery of Highly Potent, Selective, and Orally Efficacious p300/CBP Histone Acetyltransferases Inhibitors. |
| Authors of publication | Yang, Yaxi; Zhang, Rukang; Li, Zhaojun; Mei, Lianghe; Wan, Shili; Ding, Hong; Chen, Zhifeng; Xing, Jing; Feng, Huijin; Han, Jie; Jiang, Hualiang; Zheng, Mingyue; Luo, Cheng; Zhou, Bing |
| Journal of publication | Journal of medicinal chemistry |
| Year of publication | 2020 |
| a | 10.1492 ± 0.0004 Å |
| b | 10.1392 ± 0.0004 Å |
| c | 25.2626 ± 0.0011 Å |
| α | 96.515 ± 0.001° |
| β | 96.515 ± 0.001° |
| γ | 107.35° |
| Cell volume | 2435.42 ± 0.17 Å3 |
| Cell temperature | 173 K |
| Ambient diffraction temperature | 173 K |
| Number of distinct elements | 5 |
| Space group number | 1 |
| Hermann-Mauguin space group symbol | P 1 |
| Hall space group symbol | P 1 |
| Residual factor for all reflections | 0.0361 |
| Residual factor for significantly intense reflections | 0.0342 |
| Weighted residual factors for significantly intense reflections | 0.0853 |
| Weighted residual factors for all reflections included in the refinement | 0.0873 |
| Goodness-of-fit parameter for all reflections included in the refinement | 1.043 |
| Diffraction radiation wavelength | 1.54178 Å |
| Diffraction radiation type | CuKα |
| Has coordinates | Yes |
| Has disorder | No |
| Has Fobs | No |
| Revision | Date | Message | Files |
|---|---|---|---|
| 247353 (current) | 2020-01-30 | cif/ Adding structures of 1557185 via cif-deposit CGI script. |
1557185.cif |
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Users of the data should acknowledge the original authors of the
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